Iron Metabolism & Its Disorders

Iron metabolism: from health to disease.

BACKGROUND Iron is vital for almost all living organisms by participating in a wide range of metabolic processes. However, iron concentration in body tissues must be tightly regulated since excessive iron may lead to microbial infections or cause tissue damage. Disorders of iron metabolism are among the most common human diseases and cover several conditions with varied clinical manifestations....

Iron Metabolism and Its Clinical Significance

Molybdenum Cofactor Biology and Disorders Related to Its Deficiency; A Review Study

Background: Molybden, as a vital and essential micronutrient is directly involved in the metabolism of other elements including carbon, sulfur, and nitrogen. Molybdenum alone is not biologically active unless it binds to specific cofactors. Except for the bacterial nitrogenase, which contains molybdenum-Iron complex, molybdenum cofactor (Moco) is considered as the bioactive component placed in ...

Iron transport: From enterocyte to mitochondria Demir taşınımı: Enterositten mitokondriye

Transport of iron to tissues is of vital importance. Remarkable advances have been made concerning the mechanisms involving iron metabolism after its absorption. Studies assessing cellular and mitochondrial iron metabolism have resulted in interesting findings. This review highlights the recent advances in the mechanisms involving transport and delivery of iron to tissues, cellular and mitochon...

اثرات عصبی - تکاملی فقر آهن

Introduction: Deficiencies in micronutrients are a major health issue in all ages , especially children, in developing countries. Severe or long-term iron deficiency will lead to iron deficiency anemia and thus affect children’s growth and development. This review article tried to determine the neurodevelopmental effects of deficiency in this micronutrient among children. Methods: A compr...

Review on iron and its importance for human health

It is well-known that deficiency or over exposure to various elements has noticeable effects on human health. The effect of an element is determined by several characteristics, including absorption, metabolism, and degree of interaction with physiological processes. Iron is an essential element for almost all living organisms as it participates in a wide variety of metabolic processes, includin...